I was told by a friend that there is a Route 39 Scenic Byway tour spanning VA and WV. I haven't been able to find a search term to bring them all up in geocaching.com, but this link will get you started:
http://scenic39.com/?p=2131
It is not about loading the PQ's that programs like GSAK are all about. If that is all you want you shouldn't get it. I don't use it much primarily to delete caches where the last two logs are DNF which runs about six percent so I don't waste time looking. It is also very handy after doing fifty caches in a day to only have to write one log and have all of them logged with one click.
What they do is start there and take you anywhere you want with data.