My husband and I are noobs at this, but after our 4th find we vowed never to skim over the description again!
The description in question was very long and told the story of why the cacher hid something in the place he did. It was a detailed 3rd person account of his journey and method and I kind of lost interest...
The hint was something like 'when you've found the white cross, look 30cm up'. We found the cross easily enough, which was at head height but it was carved into solid, sheer rock. My husband tried scrambling up the rockface, only to fall down a few times, but there were no crevices, nothing! Tired, muddy and in a bad mood we were about to give up when I read the description and realised that when we got to the white cross, we should look at the rock face directly opposite! The cache was 30cm up from the ground, not the cross and we found it in about 5 seconds after we were facing in the right direction! How silly..
So yes, now we always read the description...