I'll respectfully disagree.
I'll respectfully disagree also.
If the ".45's" you're referring to are .45ACP, then you will do better to lay down and play dead, or you better have a Thompson machine gun and at least a 50 round magazine. If you mean .45 Long Colt with a really hot load, then you're on Te right track. a 12gauge or larger shotgun is heavy, but loaded with slugs will have a good effect, if you can get follow up shots off fast. I have spoken with a man that claimed to have survived a grizzly attack in Canada by dumping two magazines of .460 Rowland into it, the first while the bear was charging, Te second as the bear was dieing, but still attacking. I have seen video of tigers hit by very large and powerful rounds continue to charge and attack. I have heard reports from hunters, wildlife control agents, and rangers that sometimes a wild animal does not react to a gunshot the way you would expect. I have heard from coyote hunters that while hunting during a thunderstorm, sometimes the animals seem to regard the gunshot report like thunder, and appear to disregard it.
I have never heard any reports of an animal coming to the scent of the oleoresin capsicum spray bottle. This almost smacks of urban(I know, urban legend about the woods! ) legend.
I stand by my statement, condensed: This is America, If you want to carry a gun, go ahead. I feel that if you can't practice with it to be able to shoot it reliably and always hit a charging target under the sudden stress of an animal charge or attack, then you may be better off with the pepper spray. Maybe you'll feel better with both.
Me, if I'm going into bear country, I may carry a gun and the spray, but more than likely I'll just avoid any serious bear country (easiest option). I'm really just not concerned about an animal attack, it is way down on the list of problems that can occur to me out in the woods. I'm more likely to get lost or injure myslf somehow.