I'm not sure what you mean but your "profile update" pocket query. If you're talking about the "My Finds" query you can execute by selecting the "Add to Queue" button, you can only run that once a week.
I have several different PQs that I run on different days, typically on a weekly basis. I don't have more than 2 queries that run on a specific day of the week so I've also got a "Recently Placed" query set up that I can run at any time, and in a few minutes, get a download of the 50 most recently placed (in the past week) caches.
I am having the same issue with "My Finds" - have been trying since yesterday and nothing happens when I select "Add to Queue" - I have done it once before and after hitting the button, it grayed out. No such luck this time! It has been longer than 1 week since I successfully did this