When submitting my first cache last night, I was asked to select a region of the UK. I've come across this phenomenon before, and it frustrates me every time because one person's idea of "East of England" doesn't necessarily match another's. (For example, at my last address, Facebook stuck me in London while my electricity supplier said I was in the East Midlands.) Leaving aside the astoundingly obvious question of why such an otherwise well-designed website isn't capable of assigning a region automatically based upon coordinates, the easiest solution is to actually tell the user there is a map showing the region definitions geocaching.com favours, and provide a link to it. My presumably long-suffering reviewer had to message me this morning telling me my selected region was "wrong" and directing me to the map on the wiki.
A dismissive person might say the person submitting should go away and jolly-well find out this stuff. But a person who favoured user-friendly web design, pleasurable caching experience, and lightening volunteer workload would just add a link.